alternatives for Remicade

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6 days 24 minutes ago #3140 by Mora
Hello there everyone, I would really appreciate if some of you could help me a little bit, please. There’s my mother that had been receiving Remicade via IV as a treatment plan for her chronic and severe (advanced) rheumatoid arthritis. Since she has started to be on it, everything seemed to be fine and well, but that’s until earlier this week (some days ago). The problem is that she has had a severe reaction to the drug and as a result, she is not going to be able to get this drug anymore… unfortunately. The reaction was that she had tightening in her chest, and broke out in hives and others. It was an allergic reaction. It is obvious that I am currently searching for some alternatives for her and everything that you are going to share might be helpful and that’s why, please share all you know in regards to this. yeah, I also must mention here that she did has also tried Metatraxate, however this drug has caused some even worse reactions and that’s why I would need alternatives except for Metatraxate, please…
So, people… is there absolutely anything else that you can recommend trying for my mother? Maybe you know of someone who had similar reaction as my mother? What they have done? Again, anything is going to be very and very much appreciated. Thanks a lot!

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5 days 23 hours ago #3141 by Oppon
Hi there. Remicade (infliximab) it is generally a safe and usually an effective treatment for a number of inflammatory conditions, like for example the Crohn’s disease, ulcerative colitis as well as psoriatic arthritis. However, the problem is that, as much as you have already discovered it, not everyone is tolerating it so well, and there are in some cases when it may not work as well as it was expected that it would. So, in such kind of situations, there should be a healthcare provider who should recommend some alternatives for Remicade and since this is the situation you’re currently battling with, isn’t your mother’s doctor recommending anything?
Anyway, depending on the condition that is being treated, these options can include one or multiple from the following:
Some other medications, like for example corticosteroids, antidiarrheal, or antibiotics; Lifestyle changes; Surgery; Dietary changes as well as nutritional supplementation.
In my opinion all of this must be discussed with the doctor and he should be able to give an answer. They should be able on what the changes should be as well as what medication must be taken (other than Remicade and Metatraxate as you mentioned). Hopefully this would help.

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5 days 23 hours ago #3142 by Hapsylle
hi there op, it does seems that the reaction your mother has had it is because of an allergy that she had to Remicade. I see you mentioned it but, has it has been confirmed by your doctor? Has your mother seen a doctor or got the emergency treatment immediately after she has had that reaction? In addition to that, what has been said earlier by the previous poster here is also true… only her doctor is able to recommend an proper alternative medication to Remicade or your mother can take some pre medications (like for example the antihistamines) prior to Remicade infusion. And I am thinking that your mother could most likely talk about these possibilities with her doctor. Really hope she is going to be well.

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5 days 23 hours ago #3143 by Holman
Hello there… remicade, which is also being called infliximab, it is also being known as an Tumor Necrosis Factor Inhibitor (or in short you can also find TNF or TNFI) and it must be given by Intravenous (IV) Injection in a clinic under a professional doctor supervision. As it would be expected, in my opinion, approximately 17% or so of patients who have been given Remicade had bad infusion reactions which were requiring half of them to immediately stop the treatment and never start again. From as much as I have heard from a lot of people, and from all the research that I have done online, I would say that those reactions (quite the same as your mother had) are pretty much common. Well, the main reported side effect has inn found in approximately 20% of the patients those who have been receiving Remicade has been diagnosed with some skin disorders among which I can mention here either eczema or psoriasis. Sorry that I can’t actually recommend any other medication as an alternative for Remicade if your mother is among those who cannot take Remicade… but as it was said earlier, I also do think that this should be recommended by the doctor!C29

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5 days 22 hours ago #3144 by Plaun1977
hello there OP, I am not an expert and generally I can’t help you with much (if at all), but all I want to say is that you may want to look into Enbrel or Humira…. The Enbrel has been the first anti TNF drug and it has been approved nearly 20 years ago back in 1998. As for the other one, Humira, this is more recent medication but it is still quite old… I mean, this one has been approved back in 2002. Whichever the case, as I have already mentioned here, I cannot actually help you with much as I don’t know nearly anything in regards to their effectiveness, side effects, how helpful or not helpful they are and so on and so forth. I just remembered their names as I have a friend in another country who suffers from arthritis. He visited me a while back and we discussed about his arthritis. He only said that he tried these 2 drugs which I remembered their names. He said that he got help. Hopefully you are going to get some help too!

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2 days 23 hours ago #3145 by DixonK
I am also suffering from Rheumatoid Arthritis and I know that currently this disease is being reasonably well suppressed with the help of hydroxychloroquine as well as sulfasalazine and I also need to use prednisone/ prednisolone this is during the flare ups. My specialist has recommended me to try out the leflunomide that’s in case the things are going to take a turn for the worse and since that’s what the doctor has recommended me then I think it might be a good idea if I would recommend you to look at it more for your mother, you never know how it might work for her so giving it a try might come out with good results. After all we live in 2017 so I guess there should be quite enough RA medication alternatives for your mother out there. wish you both all the best!

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